Selected Publications/Patents

Smith, A.J., Larsen, T.R.B., Zimmerman, H.K., Virolainen, S. J., Meyer, J.J., Keranen-Burden, L.M., Burden, D.L.; “Design and Construction of a Multi-Tiered Minimal Actin Cortex for Structural Support in Lipid Bilayer Applications”; ACS Appl. Bio Mater., 2024, 7, 3, 1936-1946

Burden, D.L., Meyer, J.J., Michael, R.D., Anderson, S.C., Burden, H.M., Peña, S.M., Leong-Fern, K.J., Van Ye, L.A., Meyer, E.C., Keranen-Burden, L.M.; “Confirming Silent Translocation through Nanopores with Simultaneous Single-Molecule Fluorescence and Single-Channel electrical Recordings”;  Anal. Chem. 2023, 95, 49, 180020-180028

Burden, D.L., Keranen Burden, L.M., “Improved Membranes for Nanopore Sensing Applications,” PCT/US 2019/030665, Patent App., Pub. Nov. 7, 2019.

Burden, D., Kim, D., Cheng, W., Chandler Lawler, E., Dreyer, D., Keranen Burden, L., Mechanically Enhancing Planar Lipid Bilayers with a Minimal Actin Cortex, Langmuir, 34, 10847-10855, 2018.

Burden, D.L., Keranen-Burden, L.M., “Monitoring and Controlling the Delivery of Single Molecules through Nanopores,” Scientia, 115, 32-35, ISSN 2059-8971, 2017.

Kasianowicz, J. Reiner, J, Balijepalli, A., Robertson, J., Burden, D.L., Burden, L., “Systems and Methods for Controlling Temperature of Small Volumes,” Patent No. 9500610, App. No. 14/073,126; Pub. No. 20140064324, United States, issued 11/2016.

Pederson, E.D, Barbalas, J., Drown, B.S., Culbertson, M.J., Keranen Burden, L.M., Kasianowicz, J.J., Burden, D.L., “Proximal Capture Dynamics for a Single Biological Nanopore Sensor,” J. Phys. Chem. B, 119, 10448-10445, 2015.

Reiner, J., Robertson, J.W.F., Keranen Burden, L.M., Balijepalli, A., Burden, D.L., Kasianowicz, J., “Temperature Sculpting in Yactoliter Volumes,” J. Am. Chem. Soc., 135, 3087-3094, 2013.

Reiner, J., Balijepalli, A. Robertson, J., Drown, B., Burden, D.L., Kasianowicz, J., “The Effects of Diffusion on an Exonuclease/Nanopore-Based DNA Sequencing Engine,” J. Chem. Phys., 137, 214903, 2012.

Lam, J, Culbertson, M.J., Skinner, N.P. Barton, Z., Burden, D.L., “Information Content in Fluorescence Correlation Spectroscopy: Binary Mixtures and Detection Volume Distortion,” Anal. Chem., 83, 5268-5274, 2011.

Bailey, D.J., Kindt, J.T., Taylor, M.M., Paulson, A.R., Jones, B.H., Hubbell, K.L., Keranen-Burden, L.M., Burden, D.L., “Post-hoc Vibration Mitigation for Single-Molecule Tracking and Diffusion Measurements in Lipid Membranes”, Spetrosc. Lett., 43, 586-596, 2010.

Reiner, J., Jahn, A., Stavis, S. Culbertson, M., Vreeland, W., Burden, D., Geist, J., Gaitan, M., “Accurate Optical Analysis of Single Molecule Entrapment in Nanoscale Vesicles”, Anal. Chem., 82,180-188, 2010.

Carr, J., Himes, R.D., Keung, C.H., Burden, D.L., Walhout, P.W., “Heterogeneous Translational Dynamics of Rhodamine B in Polyelectrolyte Multilayer Thin Films Observed by Single Molecule Microscopy,” Langmuir, 25, 8330-8339, 2009.

Williams, J.T.B, Culbertson, M.J., Burden, D.L., “Numerical Fluorescence Correlation Spectroscopy – A Unique Opportunity for Advancement in Biotechnological Systems Research, Am. Biotech. Lab., 26, 6, 2008.

Culbertson, M.J., Williams, J.T.B., Cheng, W., Stults, D.A, Wiebracht, E., Kasianowicz, J.J., Burden, D.L., “Numerical Fluorescence Correlation Spectroscopy for the Analysis of Molecular Dynamics under Non-standard Conditions, Anal. Chem., 79, 4031-4039, 2007.

Culbertson, M.J., Burden, D.L., “A Distributed Algorithm for Multi-tau Autocorrelation,” Rev. Sci. Inst., 78, 044102, 2007.

Chandler, E.L., Smith, A.L., Burden, L.M., Kasianowicz, J.J., Burden, D.L., “Membrane Surface Dynamics of DNA-Threaded Nanopores Revealed by Simultaneous Single-Molecule Optical and Ensemble Electrical Recording,” Langmuir, 20, 898-905, 2004.

Burden, D.L., Walhout, P.K., Elliott, J.T, Chandler, E.L., Scharf, R.G., Culbertson, M.J., Stults, D.A., Rupp, E.L., Poppen, S.D., “Measuring Diffusion in Nanoscale Environments with Single-Molecule Confocal Fluorescence Microscopy,” Spectrosc. Lett., 37, 129-149, 2004.

Elliott, J.T., Burden, D.L., Woodward, J., Seghal, A., Douglas, J., “Phospholipid Monolayers Supported on Spun Cast Polystyrene Films,” Langmuir, 19, 2275-2283, 2003.

Burden, D.L., Kasianowicz, J.J., “Diffusion Bias and Photophysical Dynamics of Single Molecules in Unsupported Lipid Bilayer Membranes Probed with Confocal Microscopy,” J. Phys. Chem. B, 104, 6103, 2000.

Burden, D.L., Kasianowicz, J.J., “Interrogating Unsupported Lipid Bilayers with Scanning Confocal Single-Molecule Fluorescence Microscopy,” Proc. SPIE, 3922, 27, 2000.

Smith, A.J., Larsen, T.R.B., Zimmerman, H.K., Virolainen, S. J., Meyer, J.J., Keranen-Burden, L.M., Burden, D.L.; “Design and Construction of a Multi-Tiered Minimal Actin Cortex for Structural Support in Lipid Bilayer Applications”; ACS Appl. Bio Mater., 2024, 7, 3, 1936-1946

Burden, D.L., Meyer, J.J., Michael, R.D., Anderson, S.C., Burden, H.M., Peña, S.M., Leong-Fern, K.J., Van Ye, L.A., Meyer, E.C., Keranen-Burden, L.M.; “Confirming Silent Translocation through Nanopores with Simultaneous Single-Molecule Fluorescence and Single-Channel electrical Recordings”;  Anal. Chem. 2023, 95, 49, 180020-180028

Burden, D.L., Keranen Burden, L.M., “Improved Membranes for Nanopore Sensing Applications,” PCT/US 2019/030665, Patent App., Pub. Nov. 7, 2019.

Burden, D., Kim, D., Cheng, W., Chandler Lawler, E., Dreyer, D., Keranen Burden, L., Mechanically Enhancing Planar Lipid Bilayers with a Minimal Actin Cortex, Langmuir, 34, 10847-10855, 2018.

Burden, D.L., Keranen-Burden, L.M., “Monitoring and Controlling the Delivery of Single Molecules through Nanopores,” Scientia, 115, 32-35, ISSN 2059-8971, 2017.

Kasianowicz, J. Reiner, J, Balijepalli, A., Robertson, J., Burden, D.L., Burden, L., “Systems and Methods for Controlling Temperature of Small Volumes,” Patent No. 9500610, App. No. 14/073,126; Pub. No. 20140064324, United States, issued 11/2016.

Pederson, E.D, Barbalas, J., Drown, B.S., Culbertson, M.J., Keranen Burden, L.M., Kasianowicz, J.J., Burden, D.L., “Proximal Capture Dynamics for a Single Biological Nanopore Sensor,” J. Phys. Chem. B, 119, 10448-10445, 2015.

Reiner, J., Robertson, J.W.F., Keranen Burden, L.M., Balijepalli, A., Burden, D.L., Kasianowicz, J., “Temperature Sculpting in Yactoliter Volumes,” J. Am. Chem. Soc., 135, 3087-3094, 2013.

Bailey, D.J., Kindt, J.T., Taylor, M.M., Paulson, A.R., Jones, B.H., Hubbell, K.L., Keranen-Burden, L.M., Burden, D.L., “Post-hoc Vibration Mitigation for Single-Molecule Tracking and Diffusion Measurements in Lipid Membranes”, Spetrosc. Lett., 43, 586-596, 2010.

Paterson, J.; Renkema, K.; Keranen-Burden, L.M.; Halleck, M.; Schlegel, R.; Williamson, P.; Daleke, D., “Lipid Specific Activation of the Murine P4-ATPase Atp8a1 (ATPaseII)”, Biochemistry, 45, 5367, 2006.

Chandler EL, Smith AL, Burden LM, Kasianowicz JJ, Burden DL, “Membrane surface dynamics of DNA-threaded nanopores revealed by simultaneous single-molecule optical and ensemble electrical recording.” Langmuir 20: 898-905, 2004.

Ho YJ, Burden LM, Hurley JH:  “Structure of the GAF domain, a ubiquitous signaling motif and a new class of cyclic GMP receptor.” The EMBO Journal  19:5288-5299, 2000.

Burden LM, Rao VD, Murray D, Ghirlando R, Doughman SD, Anderson RA, Hurley JH:  “The flattened face of type IIb phosphatidylinositol phosphate kinase binds acidic phospholipid membranes.” Biochemistry 38:15141-15149, 1999.

Keranen LM, Newton AC:  “Ca2+ differentially regulates conventional protein kinase Cs’ membrane interaction and activation.” J. Biol. Chem. 272:25959-25967, 1997.

Keranen LM, Dutil EM, Newton AC:  “Protein kinase C is regulated in vivo by three functionally  distinct phosphorylations.” Current Biology  5:1394-1403, 1995.

Dutil EM, Keranen LM, Newton AC:  “In vivo regulation of protein kinase C by trans-phosphorylation followed by autophosphorylation.” J. Biol. Chem269:29359-29362, 1994.=

Conrad R, Keranen LM, Ellington AD, Newton AC:  “Isozyme-specific inhibition of protein kinase C by RNA aptamers.” J. Biol. Chem269:32051-32054, 1994.

Newton AC, Keranen LM:  “Phosphatidyl-L-serine is necessary for protein kinase C’s high-affinity interaction with diacylglycerol-containing membranes.” Biochemistry  33:6651-6658, 1994.

Orr JW, Keranen LM, Newton AC:  “Reversible exposure of the pseudosubstrate domain of protein kinase C by phosphatidylserine and diacylglycerol.” J. Biol. Chem.  267:15263-15266, 1992.

Murthy PPN, Pliska-Matyshak G, Keranen LM, Lam P, Mueller HH, Bhuvarahamurthy N:  “Evidence of two isomers of phosphatidylinositol in plant tissue.” Plant Physiol.  98:1498-1501, 1992.

Murthy PPN, Renders JM, Keranen LM:  “Phosphoinositides in barley aleurone layers and gibberellic acid-induced changes in metabolism.” Plant Physiol.  91:1266-1269, 1989.